RESUMO
Candida albicans is the most prevalent human fungal pathogen, that is component of the commensal microbial flora of the mouth. Under certain conditions, C. albicans can cause severe diseases, septicaemia, and death. The mass of infections made by this pathogen are connected with biofilm growth. This survey highlights the pathogenicity mechanisms of C. albicans and how this may lead to the induction of a protective immune response. The survey is based on the most recent and important literature available from the Medline database.
Assuntos
Biofilmes , Candida albicans/fisiologia , Candida albicans/patogenicidade , Candidíase/microbiologia , Interações Hospedeiro-Patógeno , Epitélio/microbiologia , Humanos , Boca/microbiologia , VirulênciaRESUMO
Opportunistic oral fungal infections have spred, especially in denture wearers. Denture stomatitis is a common inflammatory reaction, multifactorial etiology, which is usually associated with Candida species, particularly Candida albicans, due to its high virulence, ability to adhere and form biofilms on oral cavity tissues and denture surfaces. This article highlights the pathogenesis, clinical presentation, and management strategies of Candida-associated denture stomatitis commonly encountered in dental practice.